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PostPosted: Tue 19:15, 15 Mar 2011    Post subject: moncler outlet 早期应&#299

早期应用无创通气救治重症哮喘的价值
EP在于FEV1.O%2EF的升高对治疗前有显著性差异(尸<0.05),5.2±2.8emil20。(4)减轻胸内负压过度波动时对血流两组治疗前PEF.FEV1相比无显著性差异(O.O5)。动力学的不良影响。本研究48例中,2,例因气道分田_嘉,泌物过多,或无法配合无创呼吸机治疗,在治疗开始买验组58.1±7.81.4~10-223.3~6-83.6~1.84.7±1.6”1.1+0.9‘对照组59.4~6.872.1±8.5料12.7+9-23.8---0.94.4~1.30.6+0.8注与对照组相比P<0.05,[link widoczny dla zalogowanych],与治疗前相比(0.01,与对照组相比P>O.052.4并发症:观察坚持行无创通气的病人中,[link widoczny dla zalogowanych],8例出现眼睛干涩(334%),4例出现鼻部皮肤红肿(18.2%),[link widoczny dla zalogowanych],4例出现腹胀(18.2%),未出现气胸,纵膈气肿,呕吐心跳停止及吸入性肺炎等严重并发症3讨论重症支气管哮喘是一种严重威胁生命的疾病.短时间内就进入危重状态并发呼吸衰竭,病死率高。重症哮喘发作时由于气管严重痉挛.加之气道的黏液痰栓引起气道阻塞.使通气/血流比例失调和弥散下降,以及氧分压下降,[link widoczny dla zalogowanych],二氧化碳分压上升和酸中毒,[link widoczny dla zalogowanych],有研究表明广泛气道阻塞可以使PEEPi增加到9~19cmHO,导致呼吸功进一步上升.并导致呼吸机疲劳,低血压,心律失常此时应用BiPAP以克服气道高压减少呼吸机作功.改善呼吸机疲劳.降低氧耗,及减少二氧化碳产生。其机制为:(1)扩张支气管,降低气道阻力,如7cmH20PEEP,可使小支气管直径增加1mm,而使中等大小支气管扩张2ram.明2h内二氧化碳明显上升改用气管插管外,其余病人均抢救成功国外有资料报道:伴二氧化碳升高的病人中大概有3~8%需气管插管.与本资料大致相同。22例行无创通气的病人,平均2h后症状、体征及血气分析均有不同程度的改善.资料中8h.48h血气分析.第5d的肺功能等指标均有不同程度的好转.提示BiPAP呼吸机治疗哮喘是有效的。在内科治疗基础上早期使用无创通气可以挽救重症哮喘病人的生命,可减少相关并发症。但应注意掌握适应症.对于严重二氧化碳潴留,气道分泌物过多自主呼吸弱昏迷的病人宜早期运用无创通气总之.合理应用无创通气救治重症哮喘疗效好、安全性高、耐受好,值得临床推广和应用4
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