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Umbilical cord blood lead levels and neurobehavioral development of infants


Price,[link widoczny dla zalogowanych], having moved, meals and other reasons lost 32. The average blood lead level of children lost to (O.48 ± 0.15) / ~ mol / L, compared with the overall sample was no significant difference (P> 0.05). 2.3 respectively 0.72,0.48 and 0.24 / ~ mol / L as a dividing line, the 988 infants were divided into high and low lead group, compared two groups of MDI and PDI and the statistical results in Table 1 . Table 1 Infant cord blood lead levels and neurobehavioral development of the relationship between indicators (± s) 3 discussions 9O since, many foreign studies have shown that blood lead levels in the 0.48 / ~ mol / L or more that could have a negative impact on child development [1]. Control and Prevention, National Center for childhood lead poisoning in 1991, to develop diagnostic criteria for blood lead level ≥ 0.48 / ~ mol / L (with or without clinical manifestations and biochemical changes.) This standard has been accepted by scholars around the world. Due to environmental lead pollution, and social factors, education and other backgrounds, children can also lead to differences in susceptibility to lead poisoning. Thus, according to the international standard in the verification of applicability is desirable. Babies born before and after the period is the most rapid development of the nervous system, but also the period most vulnerable to damage to the baby as the research object,[link widoczny dla zalogowanych], the best indicator of lead on the development of damage. Lead in umbilical cord blood are usually less susceptible to external factors,[link widoczny dla zalogowanych], we chose to reflect before and after birth as the indicator of lead exposure standard. 3 months old, basically reflecting the developmental level of neuropsychological development of the level before and after birth, by the outside world such as biological and non biological disturbance,[link widoczny dla zalogowanych], quantitative analysis, this study objectively reflect the effects of lead on infant development. Studies have shown that cord blood lead level ≥ 0.48 / ~ mol / L of the baby, 3 months old, MDL,[link widoczny dla zalogowanych], and PDI was significantly lower than blood lead level <0.48 / ~ mol / L are, respectively, a difference of 5 points and 1O points, the difference was statistically significant (P <0.01). Accordingly shows the object being investigated, the umbilical cord blood lead levels greater than 0.48 / ~ mol / L can indeed adversely affect the infant. To lead 0.72,0.48 and 0.24 / ~ mol / L for the line, and development of the relationship between blood lead was found, with the dividing line down, high and low difference between the lead group gradually reduced, when the line moves down to 0.24 / ~ mol / I below, MDI and PDI was no statistical difference between the two. The results show that when the umbilical cord blood lead ≥ 0.48 / ~ mol / L when the baby really can adversely affect neurobehavioral development, while the international diagnostic criteria are also applicable in our country. It should be noted that the effects of lead on the development of a dose effect of a continuous process Ⅲ, to 0.48 / ~ mol / L as the diagnostic criteria for lead poisoning in children is a clinical and research workers in human development based on available information, and does not mean blood lead levels below 0.48/Jmol/L is the safe range, no adverse effects in babies. The results suggest that: even if the line moves down to 0.24 / ~ mol / L, high-lead children's MDI and PDI group is still lower than the low lead group, blood lead and the negative correlation between growth still exist, these phenomena suggest Our current environmental lead pollution has posed a threat to the health of children.
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